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KMID : 0388220140210050270
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Journal of the Korean Rheumatism Association
2014 Volume.21 No. 5 p.270 ~ p.273
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Renal Infarction in Antiphospholipid Antibody-negative Pediatric Systemic Lupus Erythematosus Patient
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Kim Si-Hye
Choe Jung-Yoon
Kim Seong-Kyu
Park Sung-Hoon
Baek Sang-Ah
Lee Hwa-Jeong
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Abstract
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Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organ systems, and is charac-terized by the deposition of immune complexes and a large array of autoantibodies. Thrombosis is a relatively fre-quent and serious complication of SLE; however, renal in-farction in young patients with antiphospholipid anti-body-negative lupus has rarely been reported, and no pe-diatric case has been reported in Korea. A 12-year-old fe-male patient was presented to our hospital with a 3-day history of nausea, vomiting, and right flank pain. She was diagnosed with SLE and lupus nephritis two years ago and was treated with corticosteroids and hydroxychloroquine, azathioprine. Abdominal computed tomography (CT) showed renal infarction in the upper pole of the right kidney. Subcutaneous low molecular weight heparin was started, and warfarin was also started simultaneously and continued for 3 months. After 3 months, only minimal atrophic changes were seen on the abdominal CT. She is doing well by maintaining oral anticoagulant therapy and is being followed up regularly through outpatient clinic visits.
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KEYWORD
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Systemic lupus erythematous, Renal infarction, Antiphospholipid antibodies
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